Can We Prevent Cancer?

Jonathan Vellinga, MD -

Can We Prevent Cancer?

Celebrating a win in the battle against cancer gives us hope. After a lengthy, grueling battle, you, your friend, or a family member has heard the sweet music of a doctor saying, “It’s in remission!” With a nearly 70% estimated 5-year survival rate for all cancers combined (1), you likely know someone who has tangled with cancer and won!


Unfortunately, cancer is still very prevalent, as it is estimated that nearly 40% of people in the US will be diagnosed with some form of cancer in their lifetimes according to the National Cancer Institute (1). That’s a sobering statistic.


What if you could avoid that whole battle? What could you do to reduce your odds of getting cancer? Fortunately, there are many strategies to strengthen your health and place yourself in a lower-risk category. The more of these life-fortifying prevention strategies you can implement in your life, the more you stack the odds in favor of preventing cancer. By the way, stacking the odds in your favor isn’t so difficult. The strategies chosen below were specifically picked due to their ability to get a lot of return for a little effort.


What is Cancer?


Normal cells have a birth and death lifecycle. Old cells die, and new cells are created to replace them. Cancerous cells are marked by runaway cell creation which damages tissues and may travel to other parts of the body to do the same (2). Quickly growing cells in a specific spot can create a dense group called a tumor, which can then release cells that invade other parts of the body. When a tumor invades other areas besides the primary site, it is known as “metastasis.” When cancer metastasizes to organs, bones, or blood, it can interfere greatly with normal functioning, producing symptoms that, for many, can be the first indication of a problem.


The Angiogenesis Connection


Not only do cancerous cells reproduce in an out-of-control manner and create tumors, but they also develop and strengthen circulatory vessels such as capillaries to ensure a constant energy supply. This building up of a blood supply is called “angiogenesis.” Note that other processes use angiogenesis, but cancer must create new blood supplies. With all the additional cells it is producing, it needs the extra energy delivered to it by a bigger blood supply. In fact, an ever-increasing capillary supply in one small region of the body can serve as a red flag that cancer is present.


Shutting Down the Transportation System


Cancer’s primary form of fuel is glucose, a form of sugar derived from foods or made in the liver that travels in the blood to reach every part of the body. That makes it tricky to starve cancer because glucose is a major fuel for the body and appears to be the preferred fuel source for the brain.


Rather than starving cancer (and your brain) of the glucose that the blood is carrying, there is a way of shutting off the formation of capillaries that make up the blood supply to the cancerous region. This is called “anti-angiogenesis.” Scientists have discovered that some substances can cause withering of the capillary supply to cancerous cells. Without its constant supply of glucose from the blood in the capillaries, the abnormal cells can’t reproduce as quickly. Since the discovery of this mechanism for countering the growth of cancer cells, many foods and even cancer treatments have been identified as having this anti-angiogenic property. Anti-angiogenic substances continue to be a compelling research topic to this day.


Fostering vs. Inhibiting Cancer


One way to approach cancer prevention at a high level is to ask, “What kinds of things foster the growth of cancer?” Or, conversely, “what kind of things inhibits the growth of cancer?”


The strategy for reducing cancer risk then becomes one of pulling the welcome mat away: reducing things that welcome cancer growth while increasing things that deter cancer growth. Various studies indicate that chronically low vitamin D3, consistently high blood sugar, and obesity are correlated with higher cancer risk. Obesity on its own is associated with 13 different types of cancer according to the CDC (3). Fortunately, there are some very simple but powerful strategies for lowering the risk of cancer.


Ways to Counter Cancer Risk Through Nutrition


Increase Vitamin D3

Vitamin D3, also known as the “sunshine vitamin,” can act as a hormone, positively influencing many systems in the body including the immune system, cardiovascular system, and endocrine system. Almost every cell and tissue in the body needs vitamin D3, which can be supplied through food, supplements, and sunshine on the skin. Because of the many beneficial effects on the body, it has been researched in conjunction with many diseases and conditions. Researchers have found that adequate vitamin D3 levels can have a positive impact not only on decreased risk of cancer but also on depression and pain (4). Recently, researchers found more direct evidence that there is a reduction in risk for 15 different kinds of cancers when vitamin D3 presence is high in the blood (5).


Strategy:

We may test your serum 25(OH)D level, which is the amount of vitamin D3 in your blood, and determine a daily dosage that will correct any vitamin D3 deficiency. Be sure to get your D3 from a high-quality brand of supplements, as vitamin D3 supplements are fat-soluble and subject to being damaged by oxygen and heat.


People always ask about sunbathing, which is the natural way to obtain vitamin D3 from the interaction of the sun with the skin. If you are deeply deficient, it may be difficult to pull vitamin D3 levels up by mere sunbathing, and unwise to try. If you are only slightly deficient, you can try getting sun on 70% of your body (no sunscreen) for 15-20 minutes each day when the sun is directly overhead. Sunbathing is not ideal for everybody, and we will take your personal history and risk factors into consideration when creating your plan. It is wise to get re-tested periodically to assure your levels are adequate and not to supplement beyond what we recommend for your situation.


Replace cancer-feeding sugary foods with tumor-starving foods.

Controlling the level of glucose in the blood (“blood sugar”) by reducing sugar in the diet is an important part of reducing the risk of cancer. It is known that cancer needs an extraordinary amount of glucose, which can be provided by excess sugar in the diet. So, several studies have looked at diabetes in particular, which is a metabolic issue where there are consistently high blood glucose levels. In studying the relationship between diabetes to cancer, researchers Ohkuma, et. al. determined that diabetes increases the risk for all types of cancers in both women and men (6). Even if you’re not diabetic, excess sugar can be quite destructive to the body in many ways so having a lower-sugar diet can reduce the overall burden on the body and put you in a lower risk category for cancer.


While cutting down on sugar, you can replace those items with good-tasting foods that help cut off the blood flow to cancer tumors. What are these miraculous foods? Dr. William Li, a physician and scientist, introduced these foods in a famous Ted Talk slide presentation in 2010 called “Can We Eat to Starve Cancer?” The presentation slide of anti-angiogenic foods (foods that cut off the blood supply to cancerous cells) is still on the Ted Talk site. The list includes such foods as berries, green tea, garlic, olive oil, and tomatoes.


Strategies:

  • Replace sugary drinks with green tea. Sugary drinks are known to increase the risk of cancer (7), so cutting these out of your life will automatically put you in a lower risk category. Drinking green tea instead of sugary drinks will further reduce your cancer risk. Green tea has a multitude of benefits, including cutting off the blood supply to cancer (anti-angiogenic), combating arthritis and aging, and reducing inflammation (8). Be wary of bottled green tea in the grocery store because many of these have added sugar! It’s best to make your own, using organic green tea bags or loose leaves. Using filtered water can increase the benefits of this strategy.


  • Use more turmeric in cooking or drink “golden milk” made from turmeric tea. The active ingredient in turmeric, called “curcumin,” has been proven to have anti-cancer properties (9) and even appears to target cancer stem cells (10) which are believed to start and maintain tumor growths. There are many recipes for golden milk online. Choose a recipe with little or no sugar to maximize the health benefits. Alternatively, take a high-quality curcumin supplement daily from a reputable supplement company.


  • Replace sugary snacks with naturally sweet berries. Berries are chock-full of substances called phytonutrients that come from the red, blue, and purple pigments in the fruit. These phytonutrients have many benefits, including anticancer actions (11), and they combat inflammation. Try adding blackberries, raspberries, or blueberries to your routine. Cherries, red grapes, and strawberries also have healthy pigments.

  • Bonus: Choosing these tumor-starving foods over sugary foods could help you lose a little weight, which further reduces cancer risk!


Double Down on Detoxification to Lower Your Risk


Exercise Until You Sweat, Then Sweat Again Tomorrow

If you only do one thing from this whole list, choose exercise! It’s difficult to beat all the positive health outcomes from exercise. Losing weight from exercising counters obesity and can help reduce risk factors that contribute to cancer, such as high blood sugar. Exercise causes the body to consume excess glucose, so it helps directly combat diabetes and high blood sugar levels that feed cancers.


Furthermore, exercising also helps the body detoxify. Expending energy will cause pores in the skin to open up and release sweat, which is a pathway that can be used for the body to release wastes. The motion of an exercising body helps move lymph fluid around, transporting some wastes to the liver and kidneys so they can go out of the body. Deep breathing during exercise super-oxygenates cells and tissues, helping them to heal faster and also helps open the detoxification pathway through lung tissues. On top of all that, exercise can reduce mental and emotional stress by increasing endorphins, the so-called “feel good” molecules.


Strategy:

What you do for exercise doesn’t matter quite as much as consistently breaking a sweat. You don’t need to run marathons, just move your body until you work up a sweat several times a week or daily if possible. Of course, a structured exercise program could help you lose weight and build muscle. However, if gardening or playing hide-and-go-seek with your children causes you to break a sweat, then do it!

Saunas are another great ways to sweat and rid yourself of toxins. Even better, combining exercise and sauna use increases fat turnover, which releases viruses, bacteria, and toxins that are stored in fat cells (12).


Boost Your Natural Detoxification Processes

Detoxification is a frequent topic in our practice because it is so important for health. Detoxification is a general term that covers the multiple ways the body renders toxins less dangerous and purges them out of the body. The heavy lifter in detoxification is the liver, which breaks down a potentially toxic substance into pieces, or adds something to it, or both, to allow it to be safely purged from the body. These processes of the liver can be aided by oral or intravenous nutrition supplements and the use of therapeutic ozone.


Strategies:


  • Detox programs – It may be helpful to do a cleansing detox program that is designed to do a gentle cleansing of the liver, assisting the liver to work on any backlog it might have.


  • IV therapy / Ozone therapy – For those who have led an unhealthy lifestyle for many years and want to jumpstart their health, a broad and deep support for detoxification might be achieved through IV therapy or ozone therapy. Glutathione, vitamin C, or Myer’s Cocktail intravenous (IV) therapy can provide extra antioxidants to support healing and slow the damage of cells. Ozone therapy is a way to use oxygen to assist in killing microorganisms in the blood, reducing the burden on the body.


  • Get Quality Sleep Proper sleep ensures the body has time to clean out wastes and repair tissues. Sleep is so important that we’ve devoted a whole series to it. Please take some time and brush up on strategies for getting good sleep.


Go Forth and Be a Good Gatekeeper


There are many ways you can be a good gatekeeper for your body, keeping out harmful substances while allowing in others that promote vibrant health. Often, just making the conscious choice to “first do no harm” is the first step on the journey towards excellent health. Hopefully, the simple suggestions listed here are useful for you, not only to minimize cancer risk but to accelerate overall health. If you would like assistance in your journey of being an excellent gatekeeper and leading a disease-resilient life, please contact us for an appointment. After an assessment, we can craft a path forward to address your unique needs.


 

Jonathan Vellinga, M.D.

Jonathan Vellinga, MD is an Internal Medicine practitioner with a broad interest in medicine. He graduated Summa cum laude from Weber State University in Clinical Laboratory Sciences and completed his medical degree from the Medical College of Wisconsin.​


Upon graduation from medical school, he completed his Internal Medicine residency at the University of Michigan. Dr. Vellinga is board-certified with the American Board of Internal Medicine and a member of the Institute for Functional Medicine.

info@tcimedicine.com

951-383-4333

www.tcimedicine.com


 

Sources:

  1. NIH National Cancer Institute. Cancer Stat Facts: Cancer of Any Site. Retrieved June 29, 2022 from https://seer.cancer.gov/statfacts/html/all.html

  2. Mayo Clinic. Cancer. Retrieved June 29, 2022 from https://www.mayoclinic.org/diseases-conditions/cancer/symptoms-causes/syc-20370588

  3. Centers for Disease Control and Prevention. Obesity and Cancer. Retrieved June 29, 2022 from https://www.cdc.gov/cancer/obesity/index.htm

  4. Ellison, D.L., Moran, H.R. Vitamin D: Vitamin or Hormone? Nurs Clin North Am. 2021 Mar;56(1):47-57. doi: 10.1016/j.cnur.2020.10.004. Epub 2020 Dec 28. PMID: 33549285.

  5. Grant, W.B. Roles of Solar UVB and Vitamin D in Reducing Cancer Risk and Increasing Survival. Anticancer Research March 2016, 36 (3) 1357-1370

  6. Ohkuma T., Peters S., Woodward M. Sex differences in the association between diabetes and cancer: a systematic review and meta-analysis of 121 cohorts including 20 million individuals and one million events. Diabetologia. 2018 Oct;61(10):2140-2154. doi: 10.1007/s00125-018-4664-5. Epub 2018 Jul 20. PMID: 30027404; PMCID: PMC6133170.

  7. Yuting L., Li-liangzi G., Kaiyin H., Changbing H., Shaohui T. Consumption of sugar-sweetened beverages and fruit juice and human cancer: a systematic review and dose-response meta-analysis of observational studies. J Cancer. 2021; 12(10): 3077–3088. Published online 2021 Mar 21. doi: 10.7150/jca.51322. PMC8040874; PMID: 33854607

  8. Chacko S.M., Thambi P.T., Kuttan R., Nishigaki, I. Beneficial effects of green tea: a literature review. Chin Med. 2010 Apr 6;5:13. doi: 10.1186/1749-8546-5-13. PMID: 20370896; PMCID: PMC2855614.

  9. Joshi P, Joshi S, Semwal D, Bisht A, Paliwal S, Dwivedi J, Sharma S. Curcumin: An Insight into Molecular Pathways Involved in Anticancer Activity. Mini Rev Med Chem. 2021;21(17):2420-2457. doi: 10.2174/1389557521666210122153823. PMID: 33480345.

  10. Li Y., Zhang T. Targeting cancer stem cells by curcumin and clinical applications. Cancer Lett. 2014 May 1;346(2):197-205. doi: 10.1016/j.canlet.2014.01.012. Epub 2014 Jan 23. PMID: 24463298.

  11. Scarpa E.S., Ninfali, P. Phytochemicals as Innovative Therapeutic Tools against Cancer Stem Cells. Int J Mol Sci. 2015 Jul 10;16(7):15727-42. doi: 10.3390/ijms160715727. PMID: 26184171; PMCID: PMC4519921.

  12. Huppe, M., Muller, J., Schulze, J., Wernze, H., & Ohnsorge, P. (2009, December 25). Treatment of patients burdened with lipophilic toxicants: A randomized controlled trial. Retrieved December 20, 2021, from http://www.rediviva.sav.sk/51i34/133.pdf

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